Gene name:
HAVCR2 (TIM3;TIMD3) ;
Protein name:
Hepatitis A virus cellular receptor 2 (HAVcr-2) ;
Alternative:
T-cell membrane protein 3 (TIM-3) ;T-cell immunoglobulin and mucin domain-containing protein 3 (TIMD-3) ;TIM-3 ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Receptor for LGALS9.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MFSHLPFDCV | LLLLLLLLTR | SSEVEYRAEV | GQNAYLPCFY | TPAAPGNLVP |
100:
VCWGKGACPV | FECGNVVLRT | DERDVNYWTS | RYWLNGDFRK | GDVSLTIENV |
150:
TLADSGIYCC | RIQIPGIMND | EKFNLKLVIK | PAKVTPAPTR | QRDFTAAFPR |
200:
MLTTRGHGPA | ETQTLGSLPD | INLTQISTLA | NELRDSRLAN | DLRDSGATIR |
250:
IGIYIGAGIC | AGLALALIFG | ALIFKWYSHS | KEKIQNLSLI | SLANLPPSGL |
300:
ANAVAEGIRS | EENIYTIEEN | VYEVEEPNEY | YCYVSSRQQP | SQPLGCRFAM |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Rat
ELISA Kit for Human HAVcr-2
ELISA Kit for Human HAVcr-2
ELISA Kit for Human HAVcr-2
CLIA Kit for Human HAVcr-2
CLIA Kit for Human HAVcr-2
CLIA Kit for Human HAVcr-2
Polyclonal Antibody for Human HAVcr-2
Polyclonal Antibody for Human HAVcr-2
Polyclonal Antibody for Human HAVcr-2
Monoclonal Antibody for Human HAVcr-2
Monoclonal Antibody for Human HAVcr-2
Monoclonal Antibody for Human HAVcr-2
Protein for Human HAVcr-2
Protein for Human HAVcr-2
Protein for Human HAVcr-2
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT LEU-140
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT LEU-140
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Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT LEU-140
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[
Europe PMC ]
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Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT LEU-140
tissue :
Embryo .
tissue :
Umbilical cord blood .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT LEU-140
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2);VARIANT LEU-140
tissue :
Lung .
tissue :
Pancreas .
8.
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[
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION AS A RECEPTOR FOR LGALS9
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION AT THR-145;STRUCTURE OF CARBOHYDRATES;IDENTIFICATION BY MASS SPECTROMETRY